Angiogenesis in the human corpus luteum

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Angiogenesis in the corpus luteum

The corpus luteum (CL) is a site of intense angiogenesis. Within a short period, this is followed either by controlled regression of the microvascular tree in the non-fertile cycle, or maintenance and stabilisation of the new vasculature a conceptual cycle. The molecular regulation of these diverse aspects is examined. The CL provides a unique model system in which to study the cellular and mol...

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Cytokines and Angiogenesis in the Corpus Luteum

In adults, physiological angiogenesis is a rare event, with few exceptions as the vasculogenesis needed for tissue growth and function in female reproductive organs. Particularly in the corpus luteum (CL), regulation of angiogenic process seems to be tightly controlled by opposite actions resultant from the balance between pro- and antiangiogenic factors. It is the extremely rapid sequence of e...

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Angiogenesis in the human corpus luteum: changes in expression of angiopoietins in the corpus luteum throughout the menstrual cycle and in early pregnancy.

CONTEXT Blood vessel stabilization is regulated by angiopoietins and important for angiogenesis in the corpus luteum. OBJECTIVE To study angiogenesis and blood vessel stabilization in the human corpus luteum, changes in expression of angiopoietin (Ang)-1, Ang-2, and their specific receptor, Tie-2, together with the number of blood vessels and pericytes were examined in the corpus luteum throu...

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Studies on the Human Corpus Luteum

The ultrastructure of human corpora lutea obtained during the 6th, 10th, 16th, and 35th week of pregnancy is reported. Differences between the established luteal cell of pregnancy and the transitory luteal cell of the menstrual cycle are noted. In pregnancy the luteal cell is more compartmentalized into a peripheral mass of ER (endoplasmic reticulum) and a central area where mitochondria and Go...

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Biology of the Corpus luteum

Corpus luteum (CL) is a small, transient endocrine gland formed following ovulation from the secretory cells of the ovarian follicles. The main function of CL is the production of progesterone, a hormone which regulates various reproductive functions. Progesterone plays a key role in the regulation of the length of estrous cycle and in the implantation of the blastocysts. Preovulatory surge of ...

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ژورنال

عنوان ژورنال: Reproductive Medicine and Biology

سال: 2008

ISSN: 1445-5781

DOI: 10.1111/j.1447-0578.2008.00205.x